This pack covers the conceptual foundation that underpins all remaining enzyme topics.

The Topic Mastery Sheet explains the active site using the lock-and-key model, distinguishes substrate from product, and covers all three major digestive enzymes with their sites of production, substrates, and products. Bile is explicitly distinguished from a digestive enzyme - a distinction that Edexcel marks strictly. The error box targets the incorrect answer that appears repeatedly in Edexcel mark scheme rejection notes.

The Student Exam Practice Sheet (18 marks) covers: MCQ on digestion products, enzyme specificity definition, active site explanation, denaturation fill-in exercise, lock-and-key description, and a multi-part pepsin question using exam-realistic data.

The Teacher Answer Key gives accepted and rejected terminology for every key definition and includes full examiner language for the denaturation description.

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